Lab Medicine

Medicine From The Laboratory Point of View

Immunofluorescence

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Here is the famous "LE cell" test which has value only in demonstrating how the concept of autoantibodies work. The pink blobs are denatured nuclei. Here are two, with one seen being phagocytozed in the center by a PMN. This test is not nearly as sensitive as the ANA which has supplanted the LE cell test. Therefore, NEVER order an LE cell test.
Posted by Lab Medicine on October 23, 2010 Full Size| Slideshow

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